5 Key Challenges in Cryo-FIB Targeting — and How to Overcome Them
Achieving high-accuracy targeting in cryo-focused ion beam (cryo-FIB) workflows is essential for generating high-quality lamellae for cryo-electron tomography (cryo-ET). But accuracy doesn’t come easy: successful targeting requires more than a high-resolution image. At every stage in the lamella creation workflow — from identifying the region of interest (ROI) to the final milling step — multiple […]
See More with Less: Discover the Power of METEOR 2.0
We’re excited to unveil METEOR 2.0, the next evolution of our integrated cryo-fluorescence microscope (cryo-FM) designed to simplify and accelerate your cryo-electron tomography (cryo-ET) workflow. Building on the proven foundation of METEOR 1.0, the new system offers faster targeting, greater sensitivity, and enhanced ease of use, allowing researchers to confidently identify and target regions of interest—without added contamination risk or […]
The case for sensitivity in integrated fluorescence microscopes
Introduction In the rapidly evolving field of cryo-electron tomography (cryo-ET), the ability to efficiently target and image regions of interest (ROIs) within lamellae is paramount. Delmic’s integrated fluorescence microscopes, METEOR and ENZEL, have emerged as game-changers, enhancing workflow efficiency and enabling researchers to achieve unprecedented sensitivity and precision in their studies. With over 25 customers […]
