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Addressing ice contamination challenges in the Cryo-ET workflow

Delmic Must Reads

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Article By Deepak Kannan
June 6, 2024

Cryo-electron tomography (Cryo-ET) is a powerful imaging technique that enables the visualization of biomolecular structures in their near-native state at subnanometer resolutions. By combining a series of 2D images taken at different tilt angles into a 3D reconstruction, cryo-ET provides unparalleled insights into protein-protein interactions and molecular machinery within cells. This powerful technique has revolutionized […]

Article By Katherine Lau
September 7, 2026

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Uncovering the nanoscale stories that shape science.

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SPARC Spectral 3.0

By Delmic

High-performance and multimodal cathodoluminescence detector for SEM.

Gain fast and reliable access to nanoscale optical insights using, uncovering information that other analytics techniques fail to resolve.



→ Highly efficient optical design ensures maximal sensitivity and throughput

→ Large field-of-view to map large regions of interest

→ Automated and guided workflows ensures reliable data collection across users and sesions.

Compatible with: all major SEMs brands

METEOR 2.0

By Delmic

Cryo fluorescence microscope — integrated into your cryo-FIB/SEM system.

Eliminate sample transfers and guide lamella milling with precise fluorescence targeting, right inside your cryo-FIB/SEM system, thanks to its integrated fluorescence light microscope.

→ Integrated design reduces contamination risk and maximises imageable lamella area

→ Large field of view, fast-switching filter wheel, and smart tiling, stitching, and autofocus for rapid ROI identification

→ High-NA optics and a high-quantum-efficiency camera detect the faintest fluorescence at minimal excitation power, protecting lamellae from damage and devitrification

→ Easy-to-use, continually evolving software that minimises manual interaction and frees up your time

→ A future-proof system that adapts and evolves with your research in the fast-moving field of cryo-ET