Contamination free cryo-EM sample preparation

Obtain high-quality cryo-EM samples by minimizing ice contamination during sample preparation.

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Protect your sample against ice contamination

Our research indicates that nearly 40% of cryo samples become contaminated with ice. The crystalline ice formed on or within the sample can obscure the region of interest and significantly lower the cryo-EM data quality. The CERES Clean Station protects your precious sample against ice formation, enabling you to capture high-resolution structures.

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Advantages of CERES sample preparation

Moisture-free cryo-EM sample preparation

Better sample preservation

Ice-contamination free lamellae

Clean and moisture-free cryo-EM sample preparation

Prepare your cryo-EM samples in the highly effective CERES Clean Station, which provides a clean and moisture-free (< 0.01% water) environment, facilitating the preparation of grids for single particle analysis (SPA) or cryo-electron tomography (cryo-ET). The station consists of three modules specifically designed for cryo AutoGrid assembly, shuttle loading, and cassette loading.

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Explore your options

Reach out to our team of specialists to find out how the CERES Clean Station can make your sample preparation process more comfortable and more effective.

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Partners

Innovating with experts in the field

“With these powerful tools, we were able to streamline the cryo-FIB/SEM automation process. Since there is no contamination visible, we were able to polish our lamellae automatically to a thickness of less than 150 nm.”

Dr. Sebastian Tacke Max Planck Institute of Molecular Physiology

“In the TEM, contamination used to appear during tilt series acquisition, masking exposure areas and disrupting tracking focus. With the Clean Station, the entire surface of the lamellae is available for imaging, eliminating these issues.”

Jean Daraspe Université de Lausanne (UNIL)